hdzhl co., ltd

pharmaceutical raw materials,Chemical reagents, Food additives, pharmaceutical and pesticide intermediates
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th
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hdzhl co., ltd
Country:  China (Mainland)
Business Type:  Trading Company
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  • Mr.felix
  • Ms.Tina
  • Ms.Daisy
Mr.Felix
Tel: +86-13032617415
Ms.Tina
Tel: +86 18231170832
Ms.Daisy
Tel: +86-18630082079
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URL:  http://www.hdzhlc.com
City:  Handan
Street:  china
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Synephrine hydrochloride

Synephrine hydrochloride CAS NO.5985-28-4

  • Min.Order: 10 Gram
  • Payment Terms: T/T,Western Union,MoneyGram
  • Product Details

Keywords

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Quick Details

  • ProName: Synephrine hydrochloride
  • CasNo: 5985-28-4
  • Appearance: white powder
  • Application: Pharmaceutical
  • DeliveryTime: within 2-3 days after payment
  • ProductionCapacity: 500 Kilogram/Month
  • Purity: ≥98%
  • LimitNum: 10 Gram

Superiority

Synephrine Hcl(Oxedrine) is an alkaloid; synephrine produces most of its biological effects by acting as an agonist at adrenergic receptors. IC50 value: Target: adrenergic receptor agonist There is some evidence that synephrine also has weak activity at 5-HT receptors, and that it interacts with TAAR1 (trace adrenergic amine receptors). d-synephrine inhibited the uptake of [3H]-norepinephrine with an IC50 = 5.8 μM; l-synephrine was less potent (IC50 = 13.5 μM). d-Synephrine also competitively inhibited the binding of nisoxetine[m] to rat brain cortical slices, with a Ki = 4.5 μM; l-synephrine was less potent (Ki = 8.2 μM). In experiments on the release of [3H]-norepinephrine from rat brain cortical slices, however, the l-isomer of synephrine was a more potent enhancer of the release (EC50 = 8.2 μM) than the d-isomer (EC50 = 12.3 μM). This enhanced release by l-synephrine was blocked by nisoxetine.

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