hdzhl co., ltd

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Diacerein CAS NO.13739-02-1

Diacerein CAS NO.13739-02-1 CAS NO.13739-02-1

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Min.Order: 10 Gram
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Diacerein CAS NO.13739-02-1
13739-02-1; C19H12O8
Diacerein, C19H12O8

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ProName: Diacerein CAS NO.13739-02-1
CasNo: 13739-02-1
Molecular Formula: C19H12O8
Appearance: powder
Application: Pharmaceutical Intermediates
DeliveryTime: within 2-3 days after payment
PackAge: foil bags, drums or bottles ...
Port: Shanghai
ProductionCapacity: 100 Kilogram/Month
Purity: 99%
Storage: Dry and ventilated
Transportation: sea,air,express
LimitNum: 10 Gram

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Diacerein
Diacerein,C19H12O8
13739-02-1,chemical

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ProName:Diacerein
CasNo:13739-02-1
Molecular Formula:C19H12O8
Appearance:powder
Application:Pharmaceutical Intermediates
DeliveryTime:within 1-2days
PackAge:bag
Port:tianjin port
ProductionCapacity:100 Metric Ton/Month
Purity:99
Storage:dry
Transportation:by air
LimitNum:1 Gram

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product name:	diacerein
synonyms:	1,8-diacetoxy-3-carboxyanthraquinone;diacerein;diacerhein;diacetyl rhein;1,8-diacetoxyanthraquinone-3-carboxylicacid;4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylicaci;4,5-diacetylrhein;9,10-dihydro-4,5-diacetoxy-9,10-2-anthracenecarboxylicacid
cas:	13739-02-1
mf:	c19h12o8
mw:	368.29
einecs:	237-310-2
product categories:	miscellaneous biochemicals;aromatics compounds;aromatics;heterocycles;intermediates & fine chemicals;pharmaceuticals

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Diacerein Usage And Synthesis

Immunosuppressive drugs	Diacerein is a novel interleukin (IL) -1 inhibitor , the chemical name is diacetyl rhein,it is a compound of anthraquinones, the product can induce cartilage generation, it has analgesic, antipyretic and anti-inflammatory effects, but also it can significantly improve joint function in patients with osteoarthritis, and delay duration, and reduce pain to improve the quality of life of patients, it has better security, it is mainly used in clinical treatment of osteoarthritis (OA) to exert an antibacterial effect. Solubility: soluble in dimethyl sulfoxide, dimethyl acetamide; insoluble in water, methanol, chloroform. Diacerein and its active metabolite rhubarb (rhein) can reduce the generation and activity of IL-1β by inhibiting IL-1 converting enzyme. Mechanisms include: 1, inhibit the IL-1 synthesis of synovial tissue. 2, inhibit the expression of IL-1 receptor in chondrocytes . 3, inhibition of IL-1 activity. 4, repress formation of metalloproteinases such as collagenase and matrix dissolved elements and peroxide. 5, promote the synthesis of collagen and glycosaminoglycan. 6, inhibit the leukocyte chemotaxis and lysosomal stability. Diacerein does not change the cyclooxygenase activity of kidneys and platelets, and does not inhibit the synthesis of prostaglandin , so prostaglandin-dependent renal dysfunction patients can tolerate. Oral 50mg, PPB is 99%, Tmax is 2.2 h, Cmax is 3.2 mg / L, AUC is 21.3 mg • h / L, T1 / 2β is 4.3 h. Tmax and AUC values can be increased if it is administrated with food . Adverse reactions: 50% of patients suffer diarrhea, abdominal pain and loose stools. The above information is edited by the chemicalbook of Tian Ye.
Application	It is widely used in new liquid crystal polymer, engineering plastics and high-strength fibers with high performance. This product is an important osteoarthritis IL-1 inhibitor. It is used for osteoarthritis. It is a natural antioxidant, it has anti-aging, enhance immunity, removing sub-health state, physical recovery, increasing energy and body immunity effects.
Chemical Properties	Yellow Crystalline Solid
Usage	A diacetyl derivative of Rhein. Demonstrates anti-arthritic activity without inhibiting prostaglandin synthesis. Antiarthritic
Usage	antiinflammatory
Usage	A diacetyl derivative of Rhein (R318500). Demonstrates anti-arthritic activity without inhibiting prostaglandin synthesis. Antiarthritic.
Usage	Treatment of Osteoarthritis (Prevent cartilage destruction)

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HDZHL CO., LTD.who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species.

Our company is honored as the high-tech enterprise which engaged in researching, developing, manufacturing and exporting research chemicals,advanced pharmaceutical intermediates and Active Pharmaceutical Ingredients (API), include kinds of research chemicals, We have own labs to do research,we provide many kinds of research chemicals.

We have established a broad customer base in America, Australia,Russia and other European countries, We have built many long business relationship with our customers.

We base our goods with all our power so it will definitely meet and surpass every buyer's highest expectations. We guarantee that after purchasing from us , you will never look anywhere else again!

hdzhl co., ltd

Diacerein CAS NO.13739-02-1

Diacerein CAS NO.13739-02-1 CAS NO.13739-02-1

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